diff --git a/src/drivers/magnetometer/rm3100/rm3100.h b/src/drivers/magnetometer/rm3100/rm3100.h
index 7e4737d48b..3057d98c27 100644
--- a/src/drivers/magnetometer/rm3100/rm3100.h
+++ b/src/drivers/magnetometer/rm3100/rm3100.h
@@ -91,8 +91,12 @@
 #define RM3100_REVID		0x22
 
 /* interface factories */
+#if defined(CONFIG_SPI)
 extern device::Device *RM3100_SPI_interface(int bus, uint32_t devid, int bus_frequency, spi_mode_e spi_mode);
+#endif // CONFIG_SPI
+#if defined(CONFIG_I2C)
 extern device::Device *RM3100_I2C_interface(int bus, int bus_frequency);
+#endif // CONFIG_I2C
 
 #define RM3100_ADDRESS		0x20
 
diff --git a/src/drivers/magnetometer/rm3100/rm3100_i2c.cpp b/src/drivers/magnetometer/rm3100/rm3100_i2c.cpp
index 3aeba5d57e..9a7826c314 100644
--- a/src/drivers/magnetometer/rm3100/rm3100_i2c.cpp
+++ b/src/drivers/magnetometer/rm3100/rm3100_i2c.cpp
@@ -39,6 +39,8 @@
 
 #include <px4_platform_common/px4_config.h>
 
+#if defined(CONFIG_I2C)
+
 #include <assert.h>
 #include <errno.h>
 #include <stdint.h>
@@ -129,3 +131,5 @@ int RM3100_I2C::write(unsigned address, void *data, unsigned count)
 
 	return transfer(&buf[0], count + 1, nullptr, 0);
 }
+
+#endif // CONFIG_I2C
diff --git a/src/drivers/magnetometer/rm3100/rm3100_main.cpp b/src/drivers/magnetometer/rm3100/rm3100_main.cpp
index be8571cced..3c3b51060f 100644
--- a/src/drivers/magnetometer/rm3100/rm3100_main.cpp
+++ b/src/drivers/magnetometer/rm3100/rm3100_main.cpp
@@ -45,12 +45,16 @@ I2CSPIDriverBase *RM3100::instantiate(const I2CSPIDriverConfig &config, int runt
 {
 	device::Device *interface = nullptr;
 
+#if defined(CONFIG_I2C)
+
 	if (config.bus_type == BOARD_I2C_BUS) {
 		interface = RM3100_I2C_interface(config.bus, config.bus_frequency);
 
-	} else if (config.bus_type == BOARD_SPI_BUS) {
-		interface = RM3100_SPI_interface(config.bus, config.spi_devid, config.bus_frequency, config.spi_mode);
-	}
+	} else
+#endif // CONFIG_I2C
+		if (config.bus_type == BOARD_SPI_BUS) {
+			interface = RM3100_SPI_interface(config.bus, config.spi_devid, config.bus_frequency, config.spi_mode);
+		}
 
 	if (interface == nullptr) {
 		PX4_ERR("alloc failed");
@@ -93,8 +97,12 @@ extern "C" int rm3100_main(int argc, char *argv[])
 	using ThisDriver = RM3100;
 	int ch;
 	BusCLIArguments cli{true, true};
+#if defined(CONFIG_I2C)
 	cli.default_i2c_frequency = 400000;
+#endif // CONFIG_I2C
+#if defined(CONFIG_SPI)
 	cli.default_spi_frequency = 1 * 1000 * 1000;
+#endif // CONFIG_SPI
 
 	while ((ch = cli.getOpt(argc, argv, "R:")) != EOF) {
 		switch (ch) {
@@ -111,7 +119,9 @@ extern "C" int rm3100_main(int argc, char *argv[])
 		return -1;
 	}
 
+#if defined(CONFIG_I2C)
 	cli.i2c_address = RM3100_ADDRESS;
+#endif // CONFIG_I2C
 
 	BusInstanceIterator iterator(MODULE_NAME, cli, DRV_MAG_DEVTYPE_RM3100);
 
diff --git a/src/drivers/magnetometer/rm3100/rm3100_spi.cpp b/src/drivers/magnetometer/rm3100/rm3100_spi.cpp
index 3d8f84498a..b9da9f5493 100644
--- a/src/drivers/magnetometer/rm3100/rm3100_spi.cpp
+++ b/src/drivers/magnetometer/rm3100/rm3100_spi.cpp
@@ -39,6 +39,8 @@
 
 #include <px4_platform_common/px4_config.h>
 
+#if defined(CONFIG_SPI)
+
 #include <assert.h>
 #include <errno.h>
 #include <stdint.h>
@@ -135,3 +137,5 @@ int RM3100_SPI::write(unsigned address, void *data, unsigned count)
 
 	return transfer(&buf[0], &buf[0], count + 1);
 }
+
+#endif // CONFIG_SPI