diff --git a/src/lib/drivers/device/nuttx/I2C.hpp b/src/lib/drivers/device/nuttx/I2C.hpp
index 70383b5c35..affbf00c4d 100644
--- a/src/lib/drivers/device/nuttx/I2C.hpp
+++ b/src/lib/drivers/device/nuttx/I2C.hpp
@@ -44,6 +44,10 @@
 
 #include <px4_i2c.h>
 
+#if !defined(CONFIG_I2C)
+#  error I2C support requires CONFIG_I2C
+#endif
+
 namespace device __EXPORT
 {